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*[[1822]]
In the epidemic of 1822, most residents of the Pensacola area either fled or were killeddied. According to one estimate, the population was reduced from about 4000 before the epidemic to about 1400 after; a different estimate appears below. Commerce and industry were almost entirely destroyed.<ref name="bigler"/> Here are a few excerpts from eyewitness accounts of this epidemic:<ref>"1822 Yellow Fever" http://genealogytrails.com/fla/escambia/epidemic_1822.html</ref>
"A terrible epidemic has visited Pensacola... About a hundred and fifty have, in twenty days, been consigned to the tomb, and as many as eighteen have fallen in a single day. Never, perhaps, was a fever more universally fatal, utterly defying the aid of medicine; no instance of a recovery after an attack, has occurred."
